RRUNE has been showing huge volume and huge strength lately. On the weekly timeframe we can see an RSI "breakout" of a descending trendline, as well as strong candles in the price action. Upside resistance might show up at $14~ or so which is the downtrend line, then the measured move could take us to around $75. I dont expect to break out of this setup in the first go, some pullbacks are expected.
On a fundamental level, RUNE is solving some of the issues with swapping assets cross-chain which is a huge paint point in crypto currently. Their tokenomics is designed so that as the network grows in TvL (total value locked), upwards price pressure is put on the token.